Generation of two-cell cloned embryos from mouse faecal cell

The Effects of Ethanol and Strontium on Growth and Development of Two-Cell Arrested Mouse Embryos

Defective chromatin structure in somatic cell cloned mouse embryos.

Epigenetic reprogramming plays a central role in the development of cloned embryos generated by somatic cell nuclear transfer, and it is believed that aberrant reprogramming leads to the abnormal development of most cloned embryos. Recent studies show that trimethylation of H3K27 (H3K27me3) contributes to the maintenance of embryonic stem cell pluripotency because the differentiation genes are ...

Mouse embryos cloned from brain tumors.

Cancer cells escape from growth control by accumulating genetic and epigenetic alterations. In rare instances, epigenetic changes alone are oncogenic. Furthermore, agents that modify DNA methylation or chromatin structure can restore a normal phenotype to cells harboring oncogenic mutations. However, it is unclear to what extent epigenetic reprogramming can reverse oncogenesis. Using somatic nu...

P-101: Effects of Ethanol and Strontium on Growth and Development of Two-Cell Arrested Mouse Embryos

Background: Arresting in a certain step of development like two-cell stage could be one of the reasons of infertility. The aim of this study is evaluating the effects of ethanol and strontium on growth and development of two-cell arrested mouse embryos. Materials and Methods: The females were coupled with male following superovulation. Positive vaginal plug mice were killed 48 hours after hCG i...

P-102: The Effect of Strontium on Growth and Development of Two-Cell Arrested NMRI Mouse Embryos

Background: Decreasing the growth and developmental rate of embryo and arresting in certain step of development like two cell block could be the reason of infertility in some couples referring to fertility and infertility center. The aim of this study is the effect of strontium on growth and development of two-cell arrested NMRI mouse embryo. Materials and Methods: The female mice were coupled ...